PHR 520 – Advanced Instrumental Analysis

Dr. Mona Abdel Moneim

Course lecturer :

Ph. Dina Abdel Moneim

Course assistant :

The course objective to provide student with basic principles of instrumental analytical chemistry, scientific thinking and logical approach for solving problems. The quantitative analysis is mainly concerned with Chromatographic techniques including TLC and HPLC, in addition to IR Spectroscopy and mass spectroscopy.

Course objectives :

The advanced instrumental analysis is concerned with the following topics: • Theoritical principles of chromatography • Thin Layer Chromatography (theoretical principle, instrumentation and pharmaceutical application) • High Performance Liquid Chromatography (theoretical principle, instrumentation and pharmaceutical application) • Infra-red Spectrophotometry & mass spectroscopy (theoretical principle, instrumentation and pharmaceutical application) • Handling of Analysis Data (Graph construction, Calculation and Excel sheet)

Course description :

Assessment Form % Grades Mid-term 20% 40 marks Practical 20% 40 marks Interactive learning 10% 20 marks Final Written exam 40% 100 marks

Course assessment :

– “Principles of instrumental analysis 6th Ed.,D.A. skoog, F.J. holler & S.R. Crouch, (2007). – The United States Pharmacopeia, Thirty-fifth edition, The National Formulary, Thirty edition, United States Pharmacopeial Convention, Inc. , Asian Edition, Washington, D.C. (2012). – The British Pharmacopoeia, Her Majesty’s Stationery Office, London (2016).

Recommended text books :

– Sethi. HPTLC: Quantitative analysis of pharmaceutical formulation (set 3 volumes) (2013), CBS publisher. – Christopher A. Langley and Dawn Belcher. Applied pharmaceutical practice (Fasttrach) 2nd edition pharmaceutical press (2012).

Recommended refrences :